{"id":752,"date":"2019-07-22T16:59:53","date_gmt":"2019-07-22T14:59:53","guid":{"rendered":"https:\/\/www.labvet.cz\/blog\/?p=752"},"modified":"2025-03-10T23:09:08","modified_gmt":"2025-03-10T22:09:08","slug":"antibiotika-dobry-sluha-ale-spatny-pan","status":"publish","type":"post","link":"https:\/\/labvet.cz\/blog\/antibiotika-dobry-sluha-ale-spatny-pan\/","title":{"rendered":"Antibiotika – dobr\u00fd sluha, ale \u0161patn\u00fd p\u00e1n"},"content":{"rendered":"\n

Rozvoj antibiotik p\u0159inesl v uplynul\u00e9m stolet\u00ed mnoho dobr\u00e9ho do hum\u00e1nn\u00ed i veterin\u00e1rn\u00ed medic\u00edny a stal se jedn\u00edm z mezn\u00edk\u016f l\u00e9ka\u0159stv\u00ed. \u00dasp\u011b\u0161n\u00e9 zvl\u00e1d\u00e1n\u00ed infekc\u00ed tak umo\u017enilo i rozvoj dal\u0161\u00edch obor\u016f, jako chirurgie a chemoterapie. Pro\u010d tedy n\u011bkter\u00e9 pesimistick\u00e9 hlasy hovo\u0159\u00ed o dne\u0161n\u00ed dob\u011b jako o konci \u201eantibiotick\u00e9 \u00e9ry\u201c? <\/p>\n\n\n\n

Kdy\u017e v roce 1945 Sir Alexander Fleming p\u0159eb\u00edral Nobelovu cenu, u\u017e tehdy ve sv\u00e9m projevu varoval p\u0159ed vznikem rezistentn\u00edch bakteri\u00ed p\u0159i nerozumn\u00e9m u\u017e\u00edv\u00e1n\u00ed penicilinu. Barvit\u011b vyl\u00ed\u010dil fiktivn\u00ed p\u0159\u00edb\u011bh pana X, kter\u00fd si na bolest v krku koup\u00ed penicilin a u\u017e\u00edv\u00e1 ho v n\u00edzk\u00fdch d\u00e1vk\u00e1ch, tak\u017ee si vyp\u011bstuje rezistentn\u00ed streptokoky, kter\u00e9 n\u00e1sledn\u011b p\u0159enese na svou man\u017eelku. U pan\u00ed X zp\u016fsob\u00ed z\u00e1pal plic, na kter\u00fd j\u00ed je naordinov\u00e1n op\u011bt penicilin, kter\u00fd je u\u017e ale na tyto streptokoky kr\u00e1tk\u00fd a pan\u00ed um\u00edr\u00e1.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

Sir Fleming m\u011bl pravdu jen \u010d\u00e1ste\u010dn\u011b. Penicilin je st\u00e1le l\u00e9kem prvn\u00ed volby p\u0159i l\u00e9\u010db\u011b streptokok\u016f a \u00fa\u010dinkuje v\u00fdborn\u011b. Rezistentn\u00ed bakterie se v\u0161ak vytvo\u0159ily z jin\u00fdch zdroj\u016f. T\u011bmi jsou b\u011b\u017en\u00e9 bakterie, kter\u00e9 \u017eij\u00ed v n\u00e1s, na n\u00e1s i v okoln\u00edm prost\u0159ed\u00ed – Escherichia coli a tzv. ESCAPE bakterie (Enterococcus faetium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter spp., Pseudomonas spp. a Enterobacter spp.). <\/p>\n\n\n\n

Vytvo\u0159ili jsme si je nevhodn\u00fdm u\u017e\u00edv\u00e1n\u00edm antibiotik. K tomu pat\u0159\u00ed nejen v\u00fd\u0161e zm\u00edn\u011bn\u00e9 podd\u00e1vkov\u00e1n\u00ed, ale i p\u0159\u00edli\u0161 \u010dast\u00e9 a p\u0159\u00edli\u0161 dlouh\u00e9 pod\u00e1v\u00e1n\u00ed nebo pou\u017eit\u00ed tehdy, kdy\u017e to v\u016fbec nen\u00ed zapot\u0159eb\u00ed. Tedy kdy\u017e se nejedn\u00e1 o bakteri\u00e1ln\u00ed infekci a nebo kdy\u017e ji lze zvl\u00e1dnout i jin\u00fdmi zp\u016fsoby, ne\u017e celkov\u00fdm pod\u00e1v\u00e1n\u00edm antibiotik.<\/p>\n\n\n\n

N\u011bkte\u0159\u00ed odborn\u00edci dnes apeluj\u00ed na vytvo\u0159en\u00ed studi\u00ed, kter\u00e9 by ur\u010dily nejkrat\u0161\u00ed mo\u017en\u00e9 doby u\u017e\u00edv\u00e1n\u00ed jednotliv\u00fdch antibiotik, aby bakterie nebyly zbyte\u010dn\u011b dlouho pod selektivn\u00edm tlakem, kter\u00fd zvy\u0161uje pravd\u011bpodobnost vzniku rezistentn\u00edch kmen\u016f. Zat\u00edm se doba pod\u00e1v\u00e1n\u00ed antibiotik \u0159\u00eddila sp\u00ed\u0161e zku\u0161enostmi a ze strachu ze selh\u00e1n\u00ed l\u00e9\u010dby se nech\u00e1vala pro jistotu del\u0161\u00ed. Zat\u00edmco to, \u017ee kr\u00e1tk\u00e9 pod\u00e1v\u00e1n\u00ed antibiotik vede k rezistenci, nebylo potvrzeno, o negativn\u00edm vlivu dlouh\u00e9ho pod\u00e1v\u00e1n\u00ed se v\u00ed s jistotou.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

Farmaceutick\u00e9 firmy se dnes do v\u00fdvoje nov\u00fdch l\u00e1tek s antimikrobn\u00edmi \u00fa\u010dinky nehrnou, tak\u017ee t\u011bch, co m\u00e1me, si mus\u00edme v\u00e1\u017eit a u\u017e\u00edvat jich s rozmyslem. Toto v\u0161e plat\u00ed pro hum\u00e1nn\u00ed i pro veterin\u00e1rn\u00ed medic\u00ednu.<\/p>\n\n\n\n

Klasick\u00e9 bakteriologick\u00e9 vy\u0161et\u0159en\u00ed nen\u00ed drah\u00e9 a p\u0159itom n\u00e1m poskytne \u0159adu u\u017eite\u010dn\u00fdch informac\u00ed. Tedy p\u0159edev\u0161\u00edm jedn\u00e1-li se v\u016fbec o bakteri\u00e1ln\u00ed onemocn\u011bn\u00ed a d\u00e1le, kter\u00e1 antibiotika m\u016f\u017eeme pou\u017e\u00edt a kter\u00fdm se velk\u00fdm obloukem vyhnout. Laborato\u0159 m\u00e1 k dispozici dostatek dat, tak\u017ee dok\u00e1\u017ee upozornit na vznik rezistence u ur\u010dit\u00fdch antibiotik a poradit vhodnou l\u00e9\u010dbu. V ka\u017ed\u00e9 zemi m\u016f\u017ee b\u00fdt situace jin\u00e1, proto je zapot\u0159eb\u00ed b\u00fdt v kontaktu s lok\u00e1ln\u00ed laborato\u0159\u00ed a s jej\u00ed pomoc\u00ed \u0159\u00eddit l\u00e9\u010dbu.<\/p>\n\n\n\n

\n\n\n\n
\"\"<\/a><\/figure>\n","protected":false},"excerpt":{"rendered":"

Rozvoj antibiotik p\u0159inesl v uplynul\u00e9m stolet\u00ed mnoho dobr\u00e9ho do hum\u00e1nn\u00ed i veterin\u00e1rn\u00ed medic\u00edny a stal se jedn\u00edm z mezn\u00edk\u016f l\u00e9ka\u0159stv\u00ed. \u00dasp\u011b\u0161n\u00e9 zvl\u00e1d\u00e1n\u00ed infekc\u00ed tak umo\u017enilo i rozvoj dal\u0161\u00edch obor\u016f, jako chirurgie a chemoterapie. Pro\u010d tedy n\u011bkter\u00e9 pesimistick\u00e9 hlasy hovo\u0159\u00ed o dne\u0161n\u00ed dob\u011b jako o konci \u201eantibiotick\u00e9 \u00e9ry\u201c? Kdy\u017e v roce 1945 Sir Alexander Fleming p\u0159eb\u00edral … <\/p>\n

Pokra\u010dovat ve \u010dten\u00ed „Antibiotika – dobr\u00fd sluha, ale \u0161patn\u00fd p\u00e1n“<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":765,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"none","_seopress_titles_title":"Antibiotika \u2013 dobr\u00fd sluha, ale \u0161patn\u00fd p\u00e1n | Labvet.cz","_seopress_titles_desc":"Jak vybrat antibiotika? Bakteriologick\u00e9 vy\u0161et\u0159en\u00ed nen\u00ed drah\u00e9 a m\u00e1te v\u011bt\u0161\u00ed jistotu, \u017ee l\u00e9ky opravdu zaberou.","_seopress_robots_index":"","footnotes":""},"categories":[6,126],"tags":[],"class_list":["post-752","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-www-labvet-cz-blog-vetlaborator","category-zdravy-pes"],"yoast_head":"\nAntibiotika - dobr\u00fd sluha, ale \u0161patn\u00fd p\u00e1n - Labvet blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/labvet.cz\/blog\/antibiotika-dobry-sluha-ale-spatny-pan\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Antibiotika - dobr\u00fd sluha, ale \u0161patn\u00fd p\u00e1n - Labvet blog\" \/>\n<meta property=\"og:description\" content=\"Rozvoj antibiotik p\u0159inesl v uplynul\u00e9m stolet\u00ed mnoho dobr\u00e9ho do hum\u00e1nn\u00ed i veterin\u00e1rn\u00ed medic\u00edny a stal se jedn\u00edm z mezn\u00edk\u016f l\u00e9ka\u0159stv\u00ed. \u00dasp\u011b\u0161n\u00e9 zvl\u00e1d\u00e1n\u00ed infekc\u00ed tak umo\u017enilo i rozvoj dal\u0161\u00edch obor\u016f, jako chirurgie a chemoterapie. 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